Vir2Drug: Virus to Drug Nettworks
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  • Step 1
    Setup your framework of analysis
  • Step 2
    Create Pathogen Networks
  • Step 3
    Perform Drug Screening

Step 1: Setup your framework of analysis

Use the tools below to provide either a pathogen or proteins of interest. Press the Next button at the end of this page to move to the next step.


 HOST PROTEIN-GENE SEARCH TOOL

Use this tool to to find host related proteins or genes of interest to be included in you analysis. Write your gene or protein of interest to find the exact name as provided by the specific database.


     PATHOGEN PROTEIN-GENE SEARCH TOOL

    Use this tool to to find pathogen related proteins or genes of interest to be included in you analysis. Write your gene or protein of interest to find the exact name as provided by the specific database.


        Step 2: create ranked pathogen network

         Make sure that all the required files have been uploaded and then press the green button to create the pathogen-to-pathogen (P2P) network.

        Step 3: Drug Screening Process

         Make sure that all the required files have been uploaded and then press the green button to find candidate drugs for your pathogen under study.


          Vir2Drug: a drug repurposing tool based on pathogen commonalities

        Minadakis, G., Tomazou, M., Dietis, N., & Spyrou, G. M. (2023). Vir2Drug: a drug repurposing framework based on protein similarities between pathogens. Briefings in Bioinformatics, 24(1), bbac536.

        Department of Bioinformatics, The Cyprus Institute of Neurology & Genetics
        Version 1.0.3